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PDLIM2 regulates transcription factor activity in epithelial-to-mesenchymal transition via the COP9 signalosome

Epithelial cell differentiation and polarized migration associated with epithelial-to-mesenchymal transition (EMT) in cancer requires integration of gene expression with cytoskeletal dynamics. Here we show that the PDZ-LIM domain protein PDLIM2 (Mystique/SLIM), a known cytoskeletal protein and promo...

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Detalles Bibliográficos
Autores principales: Bowe, Rachael A., Cox, Orla T., Ayllón, Verónica, Tresse, Emilie, Healy, Nollaig C., Edmunds, Shelley J., Huigsloot, Merei, O'Connor, Rosemary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873889/
https://www.ncbi.nlm.nih.gov/pubmed/24196835
http://dx.doi.org/10.1091/mbc.E13-06-0306