A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death

Pyroptosis is proinflammatory cell death that occurs in response to certain microbes. Activation of the protease caspase-1 by molecular platforms called inflammasomes is required for pyroptosis. We performed a cellular genome-wide association study (GWAS) using Salmonella typhimurium infection of hu...

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Detalles Bibliográficos
Autores principales: Salinas, Raul E., Ogohara, Cassandra, Thomas, Monica I., Shukla, Kajal P., Miller, Samuel I., Ko, Dennis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873895/
https://www.ncbi.nlm.nih.gov/pubmed/24173717
http://dx.doi.org/10.1091/mbc.E13-06-0294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873895/
https://www.ncbi.nlm.nih.gov/pubmed/24173717
http://dx.doi.org/10.1091/mbc.E13-06-0294

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