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A cellular genome-wide association study reveals human variation in microtubule stability and a role in inflammatory cell death
Pyroptosis is proinflammatory cell death that occurs in response to certain microbes. Activation of the protease caspase-1 by molecular platforms called inflammasomes is required for pyroptosis. We performed a cellular genome-wide association study (GWAS) using Salmonella typhimurium infection of hu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873895/ https://www.ncbi.nlm.nih.gov/pubmed/24173717 http://dx.doi.org/10.1091/mbc.E13-06-0294 |