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ADAR2-Mediated Editing of miR-214 and miR-122 Precursor and Antisense RNA Transcripts in Liver Cancers

A growing list of microRNAs (miRNAs) show aberrant expression patterns in hepatocellular carcinoma (HCC), but the regulatory mechanisms largely remain unclear. RNA editing catalyzed by members of the adenosine deaminase acting on the RNA (ADAR) family could target the miRNA precursors and affect the...

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Detalles Bibliográficos
Autores principales: Liu, Wan-Hsin, Chen, Chao-Hung, Yeh, Kun-Huei, Li, Chiao-Ling, Wu, Yi-Jinn, Chen, Ding-Shinn, Chen, Pei-Jer, Yeh, Shiou-Hwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873926/
https://www.ncbi.nlm.nih.gov/pubmed/24386085
http://dx.doi.org/10.1371/journal.pone.0081922