Ipl1/Aurora Kinase Suppresses S-CDK-Driven Spindle Formation during Prophase I to Ensure Chromosome Integrity during Meiosis

Cells coordinate spindle formation with DNA repair and morphological modifications to chromosomes prior to their segregation to prevent cell division with damaged chromosomes. Here we uncover a novel and unexpected role for Aurora kinase in preventing the formation of spindles by Clb5-CDK (S-CDK) du...

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Detalles Bibliográficos
Autores principales: Newnham, Louise, Jordan, Philip W., Carballo, Jesus A., Newcombe, Sonya, Hoffmann, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873974/
https://www.ncbi.nlm.nih.gov/pubmed/24386320
http://dx.doi.org/10.1371/journal.pone.0083982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873974/
https://www.ncbi.nlm.nih.gov/pubmed/24386320
http://dx.doi.org/10.1371/journal.pone.0083982

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