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Tyrosine Phosphorylation Allows Integration of Multiple Signaling Inputs by IKKβ
Signaling regulated by NFκB and related transcription factors is centrally important to many inflammatory and autoimmune diseases, cancer, and stress responses. The kinase that directly regulates the canonical NFκB transcriptional pathway, Inhibitor of κB kinase β (IKKβ), undergoes activation by Ser...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873999/ https://www.ncbi.nlm.nih.gov/pubmed/24386391 http://dx.doi.org/10.1371/journal.pone.0084497 |