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Tyrosine Phosphorylation Allows Integration of Multiple Signaling Inputs by IKKβ

Signaling regulated by NFκB and related transcription factors is centrally important to many inflammatory and autoimmune diseases, cancer, and stress responses. The kinase that directly regulates the canonical NFκB transcriptional pathway, Inhibitor of κB kinase β (IKKβ), undergoes activation by Ser...

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Detalles Bibliográficos
Autores principales: Meyer, April N., Drafahl, Kristine A., McAndrew, Christopher W., Gilda, Jennifer E., Gallo, Leandro H., Haas, Martin, Brill, Laurence M., Donoghue, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873999/
https://www.ncbi.nlm.nih.gov/pubmed/24386391
http://dx.doi.org/10.1371/journal.pone.0084497