Investigating the Association of ApoE Genotypes with Blood-Brain Barrier Dysfunction Measured by Cerebrospinal Fluid-Serum Albumin Ratio in a Cohort of Patients with Different Types of Dementia

BACKGROUND: Since more than a decade ApoE is known to be a strong risk factor for Alzheimer's disease (AD); however, molecular pathways mediating this risk are still unclear. In recent years it has been hypothesized that ApoE might play a role in the disintegration of blood-brain barrier (BBB)....

Descripción completa

Detalles Bibliográficos
Autores principales: Karch, André, Manthey, Henrike, Ponto, Claudia, Hermann, Peter, Heinemann, Uta, Schmidt, Christian, Zerr, Inga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874026/
https://www.ncbi.nlm.nih.gov/pubmed/24386372
http://dx.doi.org/10.1371/journal.pone.0084405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874026/
https://www.ncbi.nlm.nih.gov/pubmed/24386372
http://dx.doi.org/10.1371/journal.pone.0084405

Ejemplares similares