Mutant p53 Cooperates with Knockdown of Endogenous Wild-Type p53 to Disrupt Tubulogenesis in Madin-Darby Canine Kidney Cells

Mutation of the p53 gene is the most common genetic alteration in human malignances and associated clinically with tumor progression and metastasis. To determine the effect of mutant p53 on epithelial differentiation, we developed three-dimensional culture (3-D) of Madin-Darby canine kidney (MDCK) c...

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Detalles Bibliográficos
Autores principales: Zhang, Yanhong, Yan, Wensheng, Chen, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874028/
https://www.ncbi.nlm.nih.gov/pubmed/24386484
http://dx.doi.org/10.1371/journal.pone.0085624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874028/
https://www.ncbi.nlm.nih.gov/pubmed/24386484
http://dx.doi.org/10.1371/journal.pone.0085624

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