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Reprogramming to Pluripotency through a Somatic Stem Cell Intermediate

Transcription factor-based reprogramming can lead to the successful switching of cell fates. We have recently reported that mouse embryonic fibroblasts (MEFs) can be directly reprogrammed into induced neural stem cells (iNSCs) after the forced expression of Brn4, Sox2, Klf4, and Myc. Here, we tested...

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Detalles Bibliográficos
Autores principales: Marthaler, Adele G., Tiemann, Ulf, Araúzo-Bravo, Marcos J., Wu, Guangming, Zaehres, Holm, Hyun, Jung Keun, Han, Dong Wook, Schöler, Hans R., Tapia, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874029/
https://www.ncbi.nlm.nih.gov/pubmed/24386457
http://dx.doi.org/10.1371/journal.pone.0085138