Cargando…

Reprogramming to Pluripotency through a Somatic Stem Cell Intermediate

Transcription factor-based reprogramming can lead to the successful switching of cell fates. We have recently reported that mouse embryonic fibroblasts (MEFs) can be directly reprogrammed into induced neural stem cells (iNSCs) after the forced expression of Brn4, Sox2, Klf4, and Myc. Here, we tested...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marthaler, Adele G., Tiemann, Ulf, Araúzo-Bravo, Marcos J., Wu, Guangming, Zaehres, Holm, Hyun, Jung Keun, Han, Dong Wook, Schöler, Hans R., Tapia, Natalia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874029/ https://www.ncbi.nlm.nih.gov/pubmed/24386457 http://dx.doi.org/10.1371/journal.pone.0085138

Ejemplares similares

Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency
por: Tiemann, Ulf, et al.
Publicado: (2014)

Epigenetic Aberrations Are Not Specific to Transcription Factor-Mediated Reprogramming
por: Tiemann, Ulf, et al.
Publicado: (2015)

Dissecting the role of distinct OCT4-SOX2 heterodimer configurations in pluripotency
por: Tapia, Natalia, et al.
Publicado: (2015)

Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming
por: Marthaler, Adele G., et al.
Publicado: (2016)

p53 connects tumorigenesis and reprogramming to pluripotency
por: Tapia, Natalia, et al.
Publicado: (2010)

Establishment of feeder-free culture system for human induced pluripotent stem cell on DAS nanocrystalline graphene
por: Lee, Hyunah, et al.
Publicado: (2016)

Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors
por: Hermann, Andreas, et al.
Publicado: (2016)

Sox2 Level Is a Determinant of Cellular Reprogramming Potential
por: Han, Dong Wook, et al.
Publicado: (2013)

Zfp296 Is a Novel, Pluripotent-Specific Reprogramming Factor
por: Fischedick, Gerrit, et al.
Publicado: (2012)

Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions
por: Joo, Jin Young, et al.
Publicado: (2014)

ERRATUM: Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions
por: Joo, Jin Young, et al.
Publicado: (2015)

Disclosing the crosstalk among DNA methylation, transcription factors, and histone marks in human pluripotent cells through discovery of DNA methylation motifs
por: Luu, Phuc-Loi, et al.
Publicado: (2013)

Analysis of protein coding mutations in hiPSCs and their possible role during somatic cell reprogramming
por: Ruiz, Sergio, et al.
Publicado: (2013)

Somatic Reprogramming—Above and Beyond Pluripotency
por: Meir, Yaa-Jyuhn James, et al.
Publicado: (2021)

Enhanced Ex Vivo Generation of Erythroid Cells from Human Induced Pluripotent Stem Cells in a Simplified Cell Culture System with Low Cytokine Support
por: Bernecker, Claudia, et al.
Publicado: (2019)

Induced Endothelial Cell-Integrated Liver Assembloids Promote Hepatic Maturation and Therapeutic Effect on Cholestatic Liver Fibrosis
por: Nam, Donggyu, et al.
Publicado: (2022)

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein
por: Ehrlich, Marc, et al.
Publicado: (2015)

Reprogramming competence of OCT factors is determined by transactivation domains
por: Kim, Kee-Pyo, et al.
Publicado: (2020)

A balanced Oct4 interactome is crucial for maintaining pluripotency
por: Han, Dong, et al.
Publicado: (2022)

Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein
por: Hallmann, Anna-Lena, et al.
Publicado: (2017)

Generation of Healthy Mice from Gene-Corrected Disease-Specific Induced Pluripotent Stem Cells
por: Wu, Guangming, et al.
Publicado: (2011)

Reprogramming to Pluripotency Can Conceal Somatic Cell Chromosomal Instability
por: Hamada, Masakazu, et al.
Publicado: (2012)

Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance
por: Ozmadenci, Duygu, et al.
Publicado: (2015)

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model
por: Lee, Hyunah, et al.
Publicado: (2020)

Changing POU dimerization preferences converts Oct6 into a pluripotency inducer
por: Jerabek, Stepan, et al.
Publicado: (2016)

In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors
por: Yilmazer, Açelya, et al.
Publicado: (2013)

Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells
por: Huang, Kaimeng, et al.
Publicado: (2015)

Sirt6 regulates efficiency of mouse somatic reprogramming and maintenance of pluripotency
por: Xu, Peng, et al.
Publicado: (2019)

Chromosomal aberration arises during somatic reprogramming to pluripotent stem cells
por: Liu, Xinyu, et al.
Publicado: (2020)

Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model
por: Park, Myung Rae, et al.
Publicado: (2019)

Self-Reprogramming of Spermatogonial Stem Cells into Pluripotent Stem Cells without Microenvironment of Feeder Cells
por: Lee, Seung-Won, et al.
Publicado: (2018)

bHLH Transcription Factor Math6 Antagonizes TGF-β Signalling in Reprogramming, Pluripotency and Early Cell Fate Decisions
por: Divvela, Satya Srirama Karthik, et al.
Publicado: (2019)

GAA Deficiency in Pompe Disease Is Alleviated by Exon Inclusion in iPSC-Derived Skeletal Muscle Cells
por: van der Wal, Erik, et al.
Publicado: (2017)

Comprehensive Human Transcription Factor Binding Site Map for Combinatory Binding Motifs Discovery
por: Müller-Molina, Arnoldo J., et al.
Publicado: (2012)

Chemically Induced Reprogramming of Somatic Cells to Pluripotent Stem Cells and Neural Cells
por: Biswas, Dhruba, et al.
Publicado: (2016)

DNA Replication Is an Integral Part of the Mouse Oocyte’s Reprogramming Machinery
por: Wang, Bingyuan, et al.
Publicado: (2014)

PIWI Proteins Are Dispensable for Mouse Somatic Development and Reprogramming of Fibroblasts into Pluripotent Stem Cells
por: Cheng, Ee-Chun, et al.
Publicado: (2014)

Self-Renewal and Pluripotency Acquired through Somatic Reprogramming to Human Cancer Stem Cells
por: Nagata, Shogo, et al.
Publicado: (2012)

Transient Acquisition of Pluripotency During Somatic Cell Transdifferentiation with iPSC Reprogramming Factors
por: Maza, Itay, et al.
Publicado: (2015)

Promyelocytic Leukemia Protein Is an Essential Regulator of Stem Cell Pluripotency and Somatic Cell Reprogramming
por: Hadjimichael, Christiana, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_eq4gke02jqo5d2dpmbjsfi9krh