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Random or Stochastic Monoallelic Expressed Genes Are Enriched for Neurodevelopmental Disorder Candidate Genes

Random or stochastic monoallelic expressed genes (StMA genes) represent a unique form of monoallelic expression where allelic choice is made at random early in development. The consequential clonal diversity provides opportunity for functional heterozygosity in tissues such as the brain, and can imp...

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Detalles Bibliográficos
Autores principales: Jeffries, Aaron R., Collier, David A., Vassos, Evangelos, Curran, Sarah, Ogilvie, Caroline M., Price, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874034/
https://www.ncbi.nlm.nih.gov/pubmed/24386451
http://dx.doi.org/10.1371/journal.pone.0085093