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Random or Stochastic Monoallelic Expressed Genes Are Enriched for Neurodevelopmental Disorder Candidate Genes
Random or stochastic monoallelic expressed genes (StMA genes) represent a unique form of monoallelic expression where allelic choice is made at random early in development. The consequential clonal diversity provides opportunity for functional heterozygosity in tissues such as the brain, and can imp...
Autores principales: | Jeffries, Aaron R., Collier, David A., Vassos, Evangelos, Curran, Sarah, Ogilvie, Caroline M., Price, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874034/ https://www.ncbi.nlm.nih.gov/pubmed/24386451 http://dx.doi.org/10.1371/journal.pone.0085093 |
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