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Suppression of Molecular Inflammatory Pathways by Toll-Like Receptor 7, 8, and 9 Antagonists in a Model of IL-23-Induced Skin Inflammation

Psoriasis is a complex inflammatory disease resulting from the activation of T helper (Th) 1 and Th17 cells. Recent evidence suggests that abnormal activation of Toll-like receptors (TLRs) 7, 8 and 9 contributes to the initiation and maintenance of psoriasis. We have evaluated the effects of TLR ant...

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Detalles Bibliográficos
Autores principales: Suárez-Fariñas, Mayte, Arbeit, Robert, Jiang, Weiwen, Ortenzio, Francesca S., Sullivan, Tim, Krueger, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874038/
https://www.ncbi.nlm.nih.gov/pubmed/24386404
http://dx.doi.org/10.1371/journal.pone.0084634