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A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases
The delivery of site-specific post-translational modifications to histones generates an epigenetic regulatory network that directs fundamental DNA-mediated processes and governs key stages in development. Methylation of histone H4 lysine-20 has been implicated in DNA repair, transcriptional silencin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874154/ https://www.ncbi.nlm.nih.gov/pubmed/24049080 http://dx.doi.org/10.1093/nar/gkt776 |