PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage

Amyotrophic lateral sclerosis (ALS) is associated with progressive degeneration of motor neurons. Several of the genes associated with this disease encode proteins involved in RNA processing, including fused-in-sarcoma/translocated-in-sarcoma (FUS/TLS). FUS is a member of the heterogeneous nuclear r...

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Detalles Bibliográficos
Autores principales: Rulten, Stuart L., Rotheray, Amy, Green, Ryan L., Grundy, Gabrielle J., Moore, Duncan A. Q., Gómez-Herreros, Fernando, Hafezparast, Majid, Caldecott, Keith W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874156/
https://www.ncbi.nlm.nih.gov/pubmed/24049082
http://dx.doi.org/10.1093/nar/gkt835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874156/
https://www.ncbi.nlm.nih.gov/pubmed/24049082
http://dx.doi.org/10.1093/nar/gkt835

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