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The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain
Cdc13, the telomere end-binding protein from Saccharomyces cerevisiae, is a multidomain protein that specifically binds telomeric single-stranded DNA (ssDNA) with exquisitely high affinity to coordinate telomere maintenance. Recent structural and genetic data have led to the proposal that Cdc13 is t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874162/ https://www.ncbi.nlm.nih.gov/pubmed/24057216 http://dx.doi.org/10.1093/nar/gkt843 |