siRNA enhances DNA-mediated interferon lambda-1 response through crosstalk between RIG-I and IFI16 signalling pathway

In addition to silencing specific genes, small interfering RNA (siRNA) transfection is also associated with the non-specific induction of inflammatory cytokines and type I interferon. Those so-called “off-target” effects have considerable implications for the interpretation of in vitro studies and c...

Descripción completa

Detalles Bibliográficos
Autores principales: Sui, Hongyan, Zhou, Ming, Chen, Qian, Lane, H. Clifford, Imamichi, Tomozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874163/
https://www.ncbi.nlm.nih.gov/pubmed/24049081
http://dx.doi.org/10.1093/nar/gkt844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874163/
https://www.ncbi.nlm.nih.gov/pubmed/24049081
http://dx.doi.org/10.1093/nar/gkt844

Ejemplares similares