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siRNA enhances DNA-mediated interferon lambda-1 response through crosstalk between RIG-I and IFI16 signalling pathway

In addition to silencing specific genes, small interfering RNA (siRNA) transfection is also associated with the non-specific induction of inflammatory cytokines and type I interferon. Those so-called “off-target” effects have considerable implications for the interpretation of in vitro studies and c...

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Detalles Bibliográficos
Autores principales:	Sui, Hongyan, Zhou, Ming, Chen, Qian, Lane, H. Clifford, Imamichi, Tomozumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874163/ https://www.ncbi.nlm.nih.gov/pubmed/24049081 http://dx.doi.org/10.1093/nar/gkt844

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