Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein

Infection by oncogenic viruses is a frequent cause for tumor formation as observed in cervical cancer. Viral oncoproteins cause inactivation of p53 function and false transcriptional regulation of central cell cycle genes. Here we analyze the regulation of Plk4, serving as an example of many cell cy...

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Detalles Bibliográficos
Autores principales: Fischer, Martin, Quaas, Marianne, Wintsche, Axel, Müller, Gerd A., Engeland, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874167/
https://www.ncbi.nlm.nih.gov/pubmed/24071582
http://dx.doi.org/10.1093/nar/gkt849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874167/
https://www.ncbi.nlm.nih.gov/pubmed/24071582
http://dx.doi.org/10.1093/nar/gkt849

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