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Higher-order chromatin domains link eQTLs with the expression of far-away genes

Distal expression quantitative trait loci (distal eQTLs) are genetic mutations that affect the expression of genes genomically far away. However, the mechanisms that cause a distal eQTL to modulate gene expression are not yet clear. Recent high-resolution chromosome conformation capture experiments...

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Detalles Bibliográficos
Autores principales: Duggal, Geet, Wang, Hao, Kingsford, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874174/
https://www.ncbi.nlm.nih.gov/pubmed/24089144
http://dx.doi.org/10.1093/nar/gkt857