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Covariation between homeodomain transcription factors and the shape of their DNA binding sites

Protein–DNA recognition is a critical component of gene regulatory processes but the underlying molecular mechanisms are not yet completely understood. Whereas the DNA binding preferences of transcription factors (TFs) are commonly described using nucleotide sequences, the 3D DNA structure is recogn...

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Detalles Bibliográficos
Autores principales: Dror, Iris, Zhou, Tianyin, Mandel-Gutfreund, Yael, Rohs, Remo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874178/
https://www.ncbi.nlm.nih.gov/pubmed/24078250
http://dx.doi.org/10.1093/nar/gkt862