Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks

The creation of a DNA break at a specific locus by a designer endonuclease can be harnessed to edit a genome. However, DNA breaks may engage one of several competing repair pathways that lead to distinct types of genomic alterations. Therefore, understanding the contribution of different repair path...

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Detalles Bibliográficos
Autores principales: Kuhar, Ryan, Gwiazda, Kamila S., Humbert, Olivier, Mandt, Tyler, Pangallo, Joey, Brault, Michelle, Khan, Iram, Maizels, Nancy, Rawlings, David J., Scharenberg, Andrew M., Certo, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874187/
https://www.ncbi.nlm.nih.gov/pubmed/24121685
http://dx.doi.org/10.1093/nar/gkt872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874187/
https://www.ncbi.nlm.nih.gov/pubmed/24121685
http://dx.doi.org/10.1093/nar/gkt872

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