Interplay between the trigger loop and the F loop during RNA polymerase catalysis

The trigger loop (TL) in the RNA polymerase (RNAP) active center plays key roles in the reactions of nucleotide addition and RNA cleavage catalyzed by RNAP. The adjacent F loop (FL) was proposed to contribute to RNAP catalysis by modulating structural changes in the TL. Here, we investigate the inte...

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Detalles Bibliográficos
Autores principales: Miropolskaya, Nataliya, Esyunina, Daria, Klimašauskas, Saulius, Nikiforov, Vadim, Artsimovitch, Irina, Kulbachinskiy, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874190/
https://www.ncbi.nlm.nih.gov/pubmed/24089145
http://dx.doi.org/10.1093/nar/gkt877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874190/
https://www.ncbi.nlm.nih.gov/pubmed/24089145
http://dx.doi.org/10.1093/nar/gkt877

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