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Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes
In eukaryotic cells, transgene expression levels may be limited by an unfavourable chromatin structure at the integration site. Epigenetic regulators are DNA sequences which may protect transgenes from such position effect. We evaluated different epigenetic regulators for their ability to protect tr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874193/ https://www.ncbi.nlm.nih.gov/pubmed/24071586 http://dx.doi.org/10.1093/nar/gkt880 |