Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity

Malaria parasites replicate asexually within their mammalian hosts as haploid cells and are subject to DNA damage from the immune response and chemotherapeutic agents that can significantly disrupt genomic integrity. Examination of the annotated genome of the parasite Plasmodium falciparum identifie...

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Detalles Bibliográficos
Autores principales: Kirkman, Laura A., Lawrence, Elizabeth A., Deitsch, Kirk W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874194/
https://www.ncbi.nlm.nih.gov/pubmed/24089143
http://dx.doi.org/10.1093/nar/gkt881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874194/
https://www.ncbi.nlm.nih.gov/pubmed/24089143
http://dx.doi.org/10.1093/nar/gkt881

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