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Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity
Malaria parasites replicate asexually within their mammalian hosts as haploid cells and are subject to DNA damage from the immune response and chemotherapeutic agents that can significantly disrupt genomic integrity. Examination of the annotated genome of the parasite Plasmodium falciparum identifie...
Autores principales: | Kirkman, Laura A., Lawrence, Elizabeth A., Deitsch, Kirk W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874194/ https://www.ncbi.nlm.nih.gov/pubmed/24089143 http://dx.doi.org/10.1093/nar/gkt881 |
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