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Epstein–Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation

Epstein–Barr virus (EBV) infects and transforms human primary B cells inducing indefinite proliferation. To investigate the potential participation of chromatin mechanisms during the EBV-mediated transformation of resting B cells we performed an analysis of global changes in histone modifications. W...

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Detalles Bibliográficos
Autores principales: Hernando, Henar, Islam, Abul B. M. M. K., Rodríguez-Ubreva, Javier, Forné, Ignasi, Ciudad, Laura, Imhof, Axel, Shannon-Lowe, Claire, Ballestar, Esteban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874198/
https://www.ncbi.nlm.nih.gov/pubmed/24097438
http://dx.doi.org/10.1093/nar/gkt886