Systematic identification of transcriptional regulatory modules from protein–protein interaction networks

Transcription factors (TFs) combine with co-factors to form transcriptional regulatory modules (TRMs) that regulate gene expression programs with spatiotemporal specificity. Here we present a novel and generic method (rTRM) for the reconstruction of TRMs that integrates genomic information from TF b...

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Detalles Bibliográficos
Autores principales: Diez, Diego, Hutchins, Andrew Paul, Miranda-Saavedra, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874207/
https://www.ncbi.nlm.nih.gov/pubmed/24137002
http://dx.doi.org/10.1093/nar/gkt913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874207/
https://www.ncbi.nlm.nih.gov/pubmed/24137002
http://dx.doi.org/10.1093/nar/gkt913

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