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Systematic identification of transcriptional regulatory modules from protein–protein interaction networks
Transcription factors (TFs) combine with co-factors to form transcriptional regulatory modules (TRMs) that regulate gene expression programs with spatiotemporal specificity. Here we present a novel and generic method (rTRM) for the reconstruction of TRMs that integrates genomic information from TF b...
| Главные авторы: | , , |
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| Формат: | Online Статья Текст |
| Язык: | English |
| Опубликовано: |
Oxford University Press
2014
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| Предметы: | |
| Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874207/ https://www.ncbi.nlm.nih.gov/pubmed/24137002 http://dx.doi.org/10.1093/nar/gkt913 |