Constitutional Nephrin Deficiency in Conditionally Immortalized Human Podocytes Induced Epithelial-Mesenchymal Transition, Supported by β-Catenin/NF-kappa B Activation: A Consequence of Cell Junction Impairment?

The kidney glomerular podocytes are the cellular target of many chronic nephropathies both determined and acquired genetically. Mutations that affected the expression and/or the function of nephrin, a key component of the slit-diaphragm, are often causes of these pathologies. Recent findings showed...

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Detalles Bibliográficos
Autores principales: Ghiggeri, Gian Marco, Gigante, Maddalena, Di Donato, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874297/
https://www.ncbi.nlm.nih.gov/pubmed/24392227
http://dx.doi.org/10.1155/2013/457490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874297/
https://www.ncbi.nlm.nih.gov/pubmed/24392227
http://dx.doi.org/10.1155/2013/457490

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