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Functional Characterization of ABCB4 Mutations Found in Low Phospholipid-Associated Cholelithiasis (LPAC)

Multidrug resistance 3 (MDR3) is expressed on the canalicular membrane of the hepatocytes and plays an important role in protecting the liver from bile acids. Altered ABCB4 gene expression can lead to a rare hepatic disease, low phospholipid-associated cholelithiasis (LPAC). In this study, we charac...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hee, Park, Hyo Jin, Choi, Ji Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874440/
https://www.ncbi.nlm.nih.gov/pubmed/24381502
http://dx.doi.org/10.4196/kjpp.2013.17.6.525