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HOXB1 restored expression promotes apoptosis and differentiation in the HL60 leukemic cell line

BACKGROUND: Homeobox (HOX) genes deregulation has been largely implicated in the development of human leukemia. Among the HOXB cluster, HOXB1 was silent in a number of analyzed acute myeloid leukemia (AML) primary cells and cell lines, whereas it was expressed in normal terminally differentiated per...

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Detalles Bibliográficos
Autores principales: Petrini, Marina, Felicetti, Federica, Bottero, Lisabianca, Errico, Maria Cristina, Morsilli, Ornella, Boe, Alessandra, De Feo, Alessandra, Carè, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874656/
https://www.ncbi.nlm.nih.gov/pubmed/24148231
http://dx.doi.org/10.1186/1475-2867-13-101