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HOXB1 restored expression promotes apoptosis and differentiation in the HL60 leukemic cell line
BACKGROUND: Homeobox (HOX) genes deregulation has been largely implicated in the development of human leukemia. Among the HOXB cluster, HOXB1 was silent in a number of analyzed acute myeloid leukemia (AML) primary cells and cell lines, whereas it was expressed in normal terminally differentiated per...
Autores principales: | Petrini, Marina, Felicetti, Federica, Bottero, Lisabianca, Errico, Maria Cristina, Morsilli, Ornella, Boe, Alessandra, De Feo, Alessandra, Carè, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874656/ https://www.ncbi.nlm.nih.gov/pubmed/24148231 http://dx.doi.org/10.1186/1475-2867-13-101 |
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