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Regulation of microRNAs by epigenetics and their interplay involved in cancer

Similar to protein-coding genes, miRNAs are also susceptible to epigenetic modulation. Although numerous miRNAs have been shown to be affected by DNA methylation, the regulatory mechanism of histone modification on miRNA is not adequately understood. EZH2 and HDACs were recently identified as critic...

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Detalles Bibliográficos
Autores principales: Liu, Xiaolan, Chen, Xiaoyan, Yu, Xinfang, Tao, Yongguang, Bode, Ann M, Dong, Zigang, Cao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874662/
https://www.ncbi.nlm.nih.gov/pubmed/24261995
http://dx.doi.org/10.1186/1756-9966-32-96