Kaposi sarcoma associated herpesvirus (KSHV) induces AKT hyperphosphorylation, bortezomib-resistance and GLUT-1 plasma membrane exposure in THP-1 monocytic cell line

BACKGROUND: Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway regulates multiple cellular processes such as cell proliferation, evasion from apoptosis, migration, glucose metabolism, protein synthesis and proper differentiation in immune cells. Kaposi sa...

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Detalles Bibliográficos
Autores principales: Gonnella, Roberta, Santarelli, Roberta, Farina, Antonella, Granato, Marisa, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874756/
https://www.ncbi.nlm.nih.gov/pubmed/24422998
http://dx.doi.org/10.1186/1756-9966-32-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874756/
https://www.ncbi.nlm.nih.gov/pubmed/24422998
http://dx.doi.org/10.1186/1756-9966-32-79

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