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Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication

BACKGROUND: Control of RNA polymerase II (RNAPII) release from pausing has been proposed as a checkpoint mechanism to ensure optimal RNAPII activity, especially in large, highly regulated genes. HIV-1 gene expression is highly regulated at the level of elongation, which includes transcriptional paus...

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Detalles Bibliográficos
Autores principales: Coiras, Mayte, Montes, Marta, Montanuy, Immaculada, López-Huertas, María Rosa, Mateos, Elena, Le Sommer, Caroline, Garcia-Blanco, Mariano A, Hernández-Munain, Cristina, Alcamí, José, Suñé, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874760/
https://www.ncbi.nlm.nih.gov/pubmed/24165037
http://dx.doi.org/10.1186/1742-4690-10-124