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T cell response specificity and magnitude against SIVmac239 are not concordant in major histocompatibility complex-matched animals

BACKGROUND: CD8+ T cell responses, restricted by major histocompatibility complex (MHC) class I molecules, are critical to controlling human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) replication. Previous studies have used MHC-matched siblings and monozygotic twin...

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Detalles Bibliográficos
Autores principales: Cain, Brian T, Pham, Ngoc H, Budde, Melisa L, Greene, Justin M, Weinfurter, Jason T, Scarlotta, Matthew, Harris, Max, Chin, Emily, O’Connor, Shelby L, Friedrich, Thomas C, O’Connor, David H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874790/
https://www.ncbi.nlm.nih.gov/pubmed/24156675
http://dx.doi.org/10.1186/1742-4690-10-116