Nitroglycerine-Induced Nitrate Tolerance Compromises Propofol Protection of the Endothelial Cells against TNF-α: The Role of PKC-β (2) and NADPH Oxidase

Continuous treatment with organic nitrates causes nitrate tolerance and endothelial dysfunction, which is involved with protein kinase C (PKC) signal pathway and NADPH oxidase activation. We determined whether chronic administration with nitroglycerine compromises the protective effects of propofol...

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Detalles Bibliográficos
Autores principales: Lei, Shaoqing, Su, Wating, Liu, Huimin, Xu, Jinjin, Xia, Zhong-yuan, Yang, Qing-jun, Qiao, Xin, Du, Yun, Zhang, Liangqing, Xia, Zhengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874952/
https://www.ncbi.nlm.nih.gov/pubmed/24396568
http://dx.doi.org/10.1155/2013/678484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874952/
https://www.ncbi.nlm.nih.gov/pubmed/24396568
http://dx.doi.org/10.1155/2013/678484

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