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In Black South Africans from Rural and Urban Communities, the 4G/5G PAI-1 Polymorphism Influences PAI-1 Activity, but Not Plasma Clot Lysis Time

Data on genetic and environmental factors influencing PAI-1 levels and their consequent effect on clot lysis in black African populations are limited. We identified polymorphisms in the promoter area of the PAI-1 gene and determined their influence on PAI-1(act) levels and plasma clot lysis time (CL...

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Detalles Bibliográficos
Autores principales: de Lange, Zelda, Rijken, Dingeman C., Hoekstra, Tiny, Conradie, Karin R., Jerling, Johann C., Pieters, Marlien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875438/
https://www.ncbi.nlm.nih.gov/pubmed/24386152
http://dx.doi.org/10.1371/journal.pone.0083151