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In Black South Africans from Rural and Urban Communities, the 4G/5G PAI-1 Polymorphism Influences PAI-1 Activity, but Not Plasma Clot Lysis Time
Data on genetic and environmental factors influencing PAI-1 levels and their consequent effect on clot lysis in black African populations are limited. We identified polymorphisms in the promoter area of the PAI-1 gene and determined their influence on PAI-1(act) levels and plasma clot lysis time (CL...
Autores principales: | de Lange, Zelda, Rijken, Dingeman C., Hoekstra, Tiny, Conradie, Karin R., Jerling, Johann C., Pieters, Marlien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875438/ https://www.ncbi.nlm.nih.gov/pubmed/24386152 http://dx.doi.org/10.1371/journal.pone.0083151 |
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