Knockdown of Hsc70-5/mortalin Induces Loss of Synaptic Mitochondria in a Drosophila Parkinson’s Disease Model

Mortalin is an essential component of the molecular machinery that imports nuclear-encoded proteins into mitochondria, assists in their folding, and protects against damage upon accumulation of dysfunctional, unfolded proteins in aging mitochondria. Mortalin dysfunction associated with Parkinson’s d...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Jun-yi, Vereshchagina, Natalia, Sreekumar, Vrinda, Burbulla, Lena F., Costa, Ana C., Daub, Katharina J., Woitalla, Dirk, Martins, L. Miguel, Krüger, Rejko, Rasse, Tobias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875477/
https://www.ncbi.nlm.nih.gov/pubmed/24386261
http://dx.doi.org/10.1371/journal.pone.0083714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875477/
https://www.ncbi.nlm.nih.gov/pubmed/24386261
http://dx.doi.org/10.1371/journal.pone.0083714

Ejemplares similares