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Knockdown of Hsc70-5/mortalin Induces Loss of Synaptic Mitochondria in a Drosophila Parkinson’s Disease Model

Mortalin is an essential component of the molecular machinery that imports nuclear-encoded proteins into mitochondria, assists in their folding, and protects against damage upon accumulation of dysfunctional, unfolded proteins in aging mitochondria. Mortalin dysfunction associated with Parkinson’s d...

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Detalles Bibliográficos
Autores principales:	Zhu, Jun-yi, Vereshchagina, Natalia, Sreekumar, Vrinda, Burbulla, Lena F., Costa, Ana C., Daub, Katharina J., Woitalla, Dirk, Martins, L. Miguel, Krüger, Rejko, Rasse, Tobias M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875477/ https://www.ncbi.nlm.nih.gov/pubmed/24386261 http://dx.doi.org/10.1371/journal.pone.0083714

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