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Constitutive Activation of STAT3 Signaling Regulates hTERT and Promotes Stem Cell-Like Traits in Human Breast Cancer Cells

Mounting clinical data suggest that high telomerase activity is tightly associated with cancer progression and poor outcomes. Constitutively activated STAT3 is found in ∼60% of human malignancies and shows a dismal prognosis. We previously reported that activated STAT3 promoted epithelial-mesenchyma...

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Detalles Bibliográficos
Autores principales: Chung, Seyung S., Aroh, Clement, Vadgama, Jaydutt V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875492/
https://www.ncbi.nlm.nih.gov/pubmed/24386318
http://dx.doi.org/10.1371/journal.pone.0083971