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Genetic Variant rs401681 at 5p15.33 Modifies Susceptibility to Lung Cancer but Not Esophageal Squamous Cell Carcinoma

BACKGROUND: The human 5p15.33 locus contains two well-known genes, the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes, which have been implicated in carcinogenesis. A common sequence variant, rs401681, located in an intronic region of CLPTM1L, h...

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Detalles Bibliográficos
Autores principales: Jiang, Man, Wu, Haijian, Qin, Chengyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875515/
https://www.ncbi.nlm.nih.gov/pubmed/24386361
http://dx.doi.org/10.1371/journal.pone.0084277