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Regulation of c-Fos Gene Expression by NF-κB: A p65 Homodimer Binding Site in Mouse Embryonic Fibroblasts but Not Human HEK293 Cells

The immediate early gene c-Fos is reported to be regulated by Elk-1 and cAMP response element-binding protein (CREB), but whether nuclear factor (NF)-κB is also required for controlling c-Fos expression is unclear. In this study, we determined how NF-κB’s coordination with Elk/serum response factor...

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Detalles Bibliográficos
Autores principales: Tu, Yu-Cheng, Huang, Duen-Yi, Shiah, Shine-Gwo, Wang, Jang-Shiun, Lin, Wan-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875526/
https://www.ncbi.nlm.nih.gov/pubmed/24386331
http://dx.doi.org/10.1371/journal.pone.0084062