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Inhibition of STAT3 Reduces Astrocytoma Cell Invasion and Constitutive Activation of STAT3 Predicts Poor Prognosis in Human Astrocytoma

Astrocytoma cells characteristically possess high invasion potentials. Recent studies have revealed that knockdown of signal transducers and activators of transcription 3 (STAT3) expression by RNAi induces apoptosis in astrocytoma cell. Nevertheless, the distinct roles of STAT3 in astrocytoma’s inva...

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Detalles Bibliográficos
Autores principales: Liang, Qinchuan, Ma, Chenkai, Zhao, Yang, Gao, Guodong, Ma, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875539/
https://www.ncbi.nlm.nih.gov/pubmed/24386409
http://dx.doi.org/10.1371/journal.pone.0084723