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Finasteride Inhibits Human Prostate Cancer Cell Invasion through MMP2 and MMP9 Downregulation

INTRODUCTION: The use of the 5-alpha reductase inhibitors (5-ARIs) finasteride and dutasteride for prostate cancer prevention is still under debate. The FDA recently concluded that the increased prevalence of high-grade tumors among 5-ARI-treated patients must not be neglected, and they decided to d...

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Detalles Bibliográficos
Autores principales: Moroz, Andrei, Delella, Flávia K., Almeida, Rodrigo, Lacorte, Lívia Maria, Fávaro, Wágner José, Deffune, Elenice, Felisbino, Sérgio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875555/
https://www.ncbi.nlm.nih.gov/pubmed/24386413
http://dx.doi.org/10.1371/journal.pone.0084757