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Deep sequencing strategies for mapping and identifying mutations from genetic screens

The development of next-generation sequencing technologies has enabled rapid and cost effective whole genome sequencing. This technology has allowed researchers to shortcut time-consuming and laborious methods used to identify nucleotide mutations in forward genetic screens in model organisms. Howev...

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Detalles Bibliográficos
Autores principales: Zuryn, Steven, Jarriault, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875646/
https://www.ncbi.nlm.nih.gov/pubmed/24778934
http://dx.doi.org/10.4161/worm.25081