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hTERT deficiency in naïve T cells affects lymphocyte homeostasis in myelodysplastic syndrome patients

Myelodysplastic syndromes (MDSs) are hematopoietic stem cell disorders with a high potential to develop into acute myeloid leukemia (AML). We have recently demonstrated that naïve T cells, but not memory T cells, from MDS patients exhibit a pronounced deficiency in the mRNA coding for the catalytic...

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Detalles Bibliográficos
Autores principales: Yang, Lili, Eksioglu, Erika A, Wei, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875656/
https://www.ncbi.nlm.nih.gov/pubmed/24386611
http://dx.doi.org/10.4161/onci.26329