Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival

It is widely accepted that anti-apoptotic Bcl-2 family members promote cancer cell survival by binding to their pro-apoptotic counterparts, thereby preventing mitochondrial outer membrane permeabilization (MOMP) and cytotoxic caspase activation. Yet, these proteins do not only function as guardians...

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Detalles Bibliográficos
Autores principales: Braun, Frédérique, de Carné Trécesson, Sophie, Bertin-Ciftci, Joséphine, Juin, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875667/
https://www.ncbi.nlm.nih.gov/pubmed/23974114
http://dx.doi.org/10.4161/cc.25972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875667/
https://www.ncbi.nlm.nih.gov/pubmed/23974114
http://dx.doi.org/10.4161/cc.25972

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